Research study shows that painkillers don't work as well when on sleep deprived subjects.
The study specifically investigated the impact of acute and chronic sleep deprivation on the sensitivity to painful and non-painful stimuli. The studies were preformed on mice. The findings of the study were stated simply: "The consequences of chronic insufficient sleep for health remain uncertain. Sleep quality and duration predict presence of pain the next day in healthy subjects suggesting that sleep disturbances alone may worsen pain, and experimental sleep deprivation in humans supports this claim."
Some of the more interesting facts about the study come in the way the mice were actually sleep deprived. Researchers 'entertained' the mice, keeping them awake. This mimicked the way most humans become sleep deprived. Team lead Chloe Alexandre, Ph.D. said, "We found that 5 consecutive days of moderate sleep deprivation can significantly exacerbate pain sensitivity over time in otherwise healthy mice. The response was specific to pain, and was not due to a state of general hyperexcitability to any stimuli." Therefore the study showed moderate sleep deprivation is as bad as severe or chronic sleep deprivation.
As for pain that is created by sleeplessness, like a groggy headache, pain killers had little or no effect on elevating this pain. As sleeplessness most times accompanies chronic pain, this is a real problem for those who get caught up in the sleep/pain cycle. The findings suggest that patients with chronic pain who use common painkillers may have to increase their dose if they are also sleep deprived or they can add a sleep aid like Nutriden Advanced Sleep Aid Supplement. Nutriden Advanced Sleep Aid supplements the brain’s natural melatonin production and introducing GABA, a neuro-inhibitor transmitter, can promote calming focus. Getting a healthy amount of sleep for the chronic pain suffer can help with their pain management. Nutriden can help with sleep problems and thereby help painkillers work.
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